And just a little more to digest: Olympus OM-D E-M5 low light high ISO sample series: Digital Photography Review DPReview has posted a series of full size jpegs of low light indoor shots. Looking at ISO 6400 jpeg at default setting, the NR is pretty apparent and destructive. The ISO 6400 with their modified settings(reduced sharpness, NR off, lower contrast) looks pretty good, even though they look a pinch soft. I think If it were me, as a JPEG shooter, I might shoot with NR and a little more sharpness applied. Even though, I'm personally impressed(as a JPEG shooter).