The only major issue I have with the image quality of my Pana GH1 is banding. With high ISO images, or any ISO images which have been underexposed and pushed, banding can be a real problem. The best solution I have found to date is Nik Dfine. The photo below is a recent ISO 1600 (more like ISO 2154 according to DxOmark data) photo I made through thick and dirty glass at a local zoo. Please ignore the reflections, which were unavoidable and do not have anything to do with the GH1 image quality. Even in this web-sized version, significant banding (both horizontal and vertical) is evident. I then used Dfine to remove the banding and added a bit of contrast in Photoshop. Below is the original, web-sized image again. If you mouseover, you will see the version after processing in Dfine: <img src="https://farm5.static.flickr.com/4033/4466287279_6ec793d6e3_o.jpg" rsrc="https://farm5.static.flickr.com/4014/4467060964_02ced925d9_o.jpg" border="0"> This debanding process does not seem to affect detail. Below is a 100% crop of the above image. Mouseover to see the same crop after debanding and a bit of contrast enhancement. <img src="https://farm3.static.flickr.com/2499/4466416355_18e8d32511_o.jpg" rsrc="https://farm5.static.flickr.com/4016/4467191012_38da6f6790_o.jpg" border="0"> Nik has a 15-day Dfine trial here. Highly recommended if you have an issue with banding. Unfortunately the Dfine plugin is not compatible with 64-bit Photoshop but works in 32-bit PS, Lightroom 2, or Aperture.