I've been researching on how to improve the noise control in ACDSee pro 7 for an ongoing series of articles I'm putting in my personal blog. Ironically, I felt the need to buy Topaz Denoise to have something to compare my results against, and some of the techniques found in DeNoise can actually be used in ACDSee Pro immediately. I would think it should work with any software that is able to de-saturate and then re-saturate a photo without losing anything color wise. When in the Develop module, make all the changes you want to a color photo. And when you are ready for noise control, in the General section, under treatment, click on Black and White. This will immediately de-saturate your photo (don't worry, the color is safe). Then go into "Detail" and make your luminance noise adjustments. It is so much easier to see the luminance noise in a B&W photo and make adjustments with the color not getting in the way of your work. When your luminance adjustment is done, go back to the General section, under treatment and click "Color". Your photo is re-saturated like it was before. Now you can go back to the Detail sub-tab and adjust for any color noise. (The noise that is left is either color noise or the luminance noise you have chosen to not address) I think it works so well because it allows you to easily identify the TYPE of noise you are dealing with in discrete steps and avoid spending time trying to find the "balance" between color and luminance noise.